Medical Physics UWA
The Impact of Observer in Pelvic Radiotherapy
By: Oliver Newland, UWA Medical Physics Masters Proposal Presentation
Supervisor: Dr Martin Ebert
The number of people who survive cancer has increased drastically over the last 40 years
as a result of the increasingly advanced treatment regimes yet the percentage of cancer
survivors who report a decline in quality of life due to treatment-induced side efects
remains high.
Specically for pelvic disease in Australia, there were approximately 40,000 annual
cases in 2019. With radiotherapy being an included treatment for at least 50% of the
cases and an incidence of toxicity requiring hospitalisation of between 15% and 20%, it
can be estimated that at least 3,000 hospitalisations due to treatment-induced genitourinary
and gastrointestinal toxicity occurred that year. Given these gures, it can
be deemed important to determine whether these negative patient treatment outcomes
are avoidable, and investigating whether the toxicity is a result of variation in observer
delineation through various NTCP model predictions is one step towards that goal.
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