Lex Fridman
A quick video on the basics of DeepMind’s AlphaFold 2 breakthrough. Please support this channel by checking out our sponsors:
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References and good blogs, articles, videos:
[1] AlphaFold 2: https://deepmind.com/blog/article/alphafold-a-solution-to-a-50-year-old-grand-challenge-in-biology
[2] AlphaFold 1: https://deepmind.com/blog/article/AlphaFold-Using-AI-for-scientific-discovery
[3] AlphaFold 1 paper: https://www.nature.com/articles/s41586-019-1923-7
[4] CASP14 Results: https://www.predictioncenter.org/casp14/zscores_final.cgi
[20] AlphaFold 2 video from Yannic Kilcher: https://www.youtube.com/watch?v=B9PL__gVxLI
[21] Science: https://www.sciencemag.org/news/2020/11/game-has-changed-ai-triumphs-solving-protein-structures
[22] Nature: https://www.nature.com/articles/d41586-020-03348-4
[23] Fortune: https://fortune.com/2020/11/30/deepmind-protein-folding-breakthrough/
OUTLINE:
0:00 – What happened?
1:03 – How big is this accomplishment?
4:39 – Proteins and amino acids
5:17 – Protein folding
8:26 – How AlphaFold 1 works
9:45 – How AlphaFold 2 works
12:09 – Why is this breakthrough important?
13:19 – Long-term future impact